laser-assisted and supercritical technologies for synthesis of new biomaterials and structures
The development and synthesis of new polymers and mineral-polymer compositions for
replacing skeletal fragments, regeneration of bone tissue, and producing matrixes
for tissue engineering are of pressing necessity.
To this end, ILIT RAS has produced a mineral-polymer composition to be used in
manufacturing biocompatible and bioactive implants having the structure similar to
that of bone tissue with the use of the laser stereolithography technique.
From a virtual model to an individual implant
The methods of laser sintering and supercritical treatment have been used to produce
3D matrixes of biopolymers from nano-porous materials
Method: Laser ablation of hydroxyapatite-based targets. Purpose: Evaporation of biocompatible and bioactive coatings on the metallic
and polymer implants to be used in stomatology, maxillofacial surgery, orthopedics,
and neurosurgery. Material: Hydroxyapatite – Ca10[PO4]6[OH]2 –
the main mineral component of bone tissue. Advantages: Universality. Low thickness (~ 1 mm)
of coatings. Controlled density and morphology. Record high adhesion at the room
temperature. Reduced probability of inflammation and immune reactions. Direct contact
of bone tissue with the implant surface. Decrease of the risk of postoperative complications.
The new methods of porous materials modification through the use of supercritical media
and by means of formation and cleanout of porous mineral-polymer compositions have been
developed with the purpose of producing the materials for the controlled regeneration of
bone tissue and advanced implants.
